abstract：:A small-cell carcinoma combined with adenocarcinoma of the gallbladder was detected in a 71-year-old Japanese woman. A nodular mass measuring 4.0 x 5.0 cm was located in the fundus of the gallbladder, in which a tiny depressed lesion measuring 2 mm in diameter was macroscopically and stereomicroscopically observed. Hi...

journal_title：Archives of pathology & laboratory medicine

authors： Nishihara K,Nagai E,Tsuneyoshi M,Nagashima M

更新日期：1994-02-01 00:00:00

abstract：:The Autopsy Committee of the College of American Pathologists has prepared this guideline in conjunction with representatives of other organizations to assist pathologists in the performance of autopsies. The guideline is to be regarded as being primarily an educational tool. Application of these recommendations on au...

journal_title：Archives of pathology & laboratory medicine

authors： Hutchins GM

更新日期：1994-01-01 00:00:00

abstract：:Apoptosis and necrosis are two fundamental types of cell death. Current knowledge indicates that the key mechanism of apoptosis is endonuclease activation leading to internucleosomal double-stranded chromatin (DNA) breaks, whereas the key mechanism of necrosis is cell membrane damage. The initial alterations of cellul...

journal_title：Archives of pathology & laboratory medicine

authors： Buja LM,Eigenbrodt ML,Eigenbrodt EH

更新日期：1993-12-01 00:00:00

abstract：:We describe a case of a 2-year-old girl with an unusual finding of amorphous hematoxyphilic substance in the pulmonary and myocardial vascular lumina. The patient had a prolonged history of intestinal obstruction necessitating extended periods of total parenteral nutrition. The patient terminally had hypercalcemia wit...

journal_title：Archives of pathology & laboratory medicine

authors： Hamoudi AC,Singley CT,Teitelbaum DH,Thornton DJ,Broner CW

更新日期：1993-12-01 00:00:00

abstract：:Revolutionary advances in technology have enhanced our understanding of the genetic changes that occur in cancer cells. This article summarizes some of the basic features of these techniques and describes their application to the identification of specific types of genetic alterations in cells. The emphasis is on thei...

journal_title：Archives of pathology & laboratory medicine

authors： Rowley JD,Aster JC,Sklar J

更新日期：1993-11-01 00:00:00

abstract：:We report the cytopathologic, immunocytochemical, histopathologic, and electron microscopic findings of a juxtaglomerular cell tumor that developed in a hypertensive 25-year-old Japanese woman. The symptoms of her disease disappeared after the tumor was resected. To our knowledge, this is the first case report of this...

journal_title：Archives of pathology & laboratory medicine

authors： Tanaka T,Okumura A,Mori H

更新日期：1993-11-01 00:00:00

abstract：:Nine pathologists from different institutions reviewed in a double-blind study 16 breast tumors previously indexed as typical medullary carcinoma, atypical medullary carcinoma, or infiltrative ductal carcinoma. A set of 16 slides was circulated two times among the nine pathologists. The diagnoses of typical and atypic...

journal_title：Archives of pathology & laboratory medicine

authors： Rigaud C,Theobald S,Noël P,Badreddine J,Barlier C,Delobelle A,Gentile A,Jacquemier J,Maisongrosse V,Peffault de Latour M

更新日期：1993-10-01 00:00:00

abstract：:A family with a syndrome consisting of granulomatous arthritis, uveitis, and rash was first described in 1985. Another family with the same syndrome was described subsequently in 1990. The condition, in both families, is clinically different from sarcoidosis. To verify whether the granulomas in such patients also coul...

journal_title：Archives of pathology & laboratory medicine

authors： de Chadarévian JP,Raphael SA,Murphy GF

更新日期：1993-10-01 00:00:00

abstract：:The autopsy is receiving renewed emphasis as a tool for quality assurance in clinical medicine. Postmortem blood cultures frequently are taken during the autopsy but are costly and of unclear diagnostic utility. To assess whether postmortem blood cultures contribute any useful information not already known from antemo...

journal_title：Archives of pathology & laboratory medicine

authors： Wilson SJ,Wilson ML,Reller LB

更新日期：1993-10-01 00:00:00

abstract：:The clinical use of ionized calcium has increased since the recognition of its importance in cardiac and critical care medicine. However, more than half the general medical centers in the United States do not provide immediate testing of ionized calcium levels in patients in critical care settings, although indication...

journal_title：Archives of pathology & laboratory medicine

authors： Kost GJ

更新日期：1993-09-01 00:00:00

abstract：:We describe a 14-year-old boy with a solitary cavernous hemangioma in the proximal small intestine that caused recalcitrant iron deficiency anemia beginning at 3 years of age. After a number of attempts to ascertain the cause of the anemia were unsuccessful, the vascular tumor was ultimately diagnosed in the jejunum, ...

journal_title：Archives of pathology & laboratory medicine

authors： Boyle L,Lack EE

更新日期：1993-09-01 00:00:00

abstract：:The College of American Pathologists and the American Society of Human Genetics offer a proficiency testing program in clinical cytogenetics. Two hundred twenty-five laboratories now provide data for this survey, which was begun in 1986. Challenges have consisted of photographed metaphases, fixed lymphoblastoid cell s...

journal_title：Archives of pathology & laboratory medicine

authors： Hoeltge GA,Dewald G,Palmer CG,David-Nelson MA,Saikevych I,Patil S,Schwartz S,Schneider NR,Herrmann M

更新日期：1993-08-01 00:00:00

abstract：:Phialemonium obovatum was found to be the cause of nosocomial osteomyelitis in a 41-year-old man after sustaining a nonpenetrating injury to his lumbar and cervical region. Histologic examination of fragments of disk and bone from L3-4 hemilaminectomy showed multiple fragments of fibrocartilage with focal necrosis, ch...

journal_title：Archives of pathology & laboratory medicine

authors： Magnon KC,Jalbert M,Padhye AA

更新日期：1993-08-01 00:00:00

abstract：:We report a case of endometrial metaplasia of the endocervix, which was associated with tubal and squamous metaplasias. The similarity to normal endometrial glands and its benign nature should be recognized, and over-diagnosis of endocervical glandular dysplasia should be avoided. ...

journal_title：Archives of pathology & laboratory medicine

authors： Yeh IT,Bronner M,LiVolsi VA

更新日期：1993-07-01 00:00:00

abstract：:We identified 100 patients (51 males and 49 females) as having the lupus anticoagulant. The following diagnoses were found in the patient population: human immunodeficiency virus positivity, 20%; systemic lupus erythematosus, 10%; prolonged preoperative activated partial thromboplastin time (APTT), 10%; procainamide h...

journal_title：Archives of pathology & laboratory medicine

authors： Clyne LP,Yen Y,Kriz NS,Breitenstein MG

更新日期：1993-06-01 00:00:00

abstract：:In this article we present a case of an ectopic gestation having morphologic features of a partial hydatidiform mole and demonstrating triploidy by flow cytometry in a patient presenting at 9 weeks' gestation. We include brief comments on partial hydatidiform mole. ...

journal_title：Archives of pathology & laboratory medicine

authors： Montgomery EA,Roberts EF,Conran RM,Hitchcock CL

更新日期：1993-06-01 00:00:00

abstract：:We report a case of spindle-cell adenosquamous carcinoma of the esophagus. This represents the third case in the worldwide literature in which an esophageal polypoid tumor contains adenosquamous carcinoma rather than the usual squamous cell carcinoma in addition to a prominent spindle-cell element. The spindle-cell co...

journal_title：Archives of pathology & laboratory medicine

authors： Orsatti G,Corvalan AH,Sakurai H,Choi HS

更新日期：1993-05-01 00:00:00

abstract：:A commercially available enzyme immunoassay (EIA) for the detection of Clostridium difficile toxin A (Premier Toxin A EIA, Meridian Diagnostics, Cincinnati, Ohio) was compared with tissue culture cytotoxicity assay, enterotoxigenic culture, and latex agglutination test for the laboratory diagnosis of C difficile-assoc...

journal_title：Archives of pathology & laboratory medicine

authors： Gilligan PH,Walden TP,Kelly WF,Wait KJ,Kraft JA,Willis DH

更新日期：1993-05-01 00:00:00

abstract：:Therapeutic drugs are not endogenous compounds. Therefore, differing reactivities between proficiency testing and patient samples have potential mechanisms beyond those attributable to alterations of the serum protein base, stabilizing materials, and other manufacturing components. The therapeutic drug monitoring prof...

journal_title：Archives of pathology & laboratory medicine

authors： Witte DL

更新日期：1993-04-01 00:00:00

abstract：:Circulating levels and cyst fluid concentrations of beta-endorphin (beta-EP), estradiol, progesterone, and prolactin were measured by radioimmunoassays in 10 premenopausal women with gross breast cysts. In addition, aspirates and frozen tissue sections from cystic lesions were investigated immunocytochemically for a p...

journal_title：Archives of pathology & laboratory medicine

authors： Schön HJ,Schurz B,Wenzl R,Knogler W,Kubista E

更新日期：1993-03-01 00:00:00

abstract：:The performance of participants on the 1990 Comprehensive Blood Bank Surveys of the College of American Pathologists was consistent with the high quality of past surveys. The surveys include challenges in ABO and Rh typing, crossmatching, transfusion decisions, unexpected antibody detection and identification, and sup...

journal_title：Archives of pathology & laboratory medicine

authors： Cooper ES,Walker RH,Schmidt PJ,Polesky HF

更新日期：1993-02-01 00:00:00

abstract：:Evidence is presented that basophilic radial hairlines in the calcified layer of articular cartilage are in vivo microcracks. They were present in three of 25 normal patellas from subjects below the age of 50 years, in 20 of 25 recently fractured hips (average patient age, 77.3 years), and in 16 of 25 osteoarthritic t...

journal_title：Archives of pathology & laboratory medicine

authors： Sokoloff L

更新日期：1993-02-01 00:00:00

abstract：:It is well known that neoplastic cells of several organs produce amylases. However, to our knowledge, alpha-amylase expression has not been reported in hepatic neoplasms. In the present study, we surveyed the expression of alpha-amylase isoenzymes in cholangiocarcinoma (CCC) (n = 18) and hepatocellular carcinoma (n = ...

journal_title：Archives of pathology & laboratory medicine

authors： Terada T,Nakanuma Y

更新日期：1993-02-01 00:00:00

abstract：:Since it is believed that "a picture is worth a thousand words," incorporation of computer-generated line art was used as a adjunct to gross description in surgical pathology reporting in selected cases. The lack of an integrated software program was overcome by using commercially available graphic and word processing...

journal_title：Archives of pathology & laboratory medicine

authors： Pillarisetti SG

更新日期：1993-01-01 00:00:00

abstract：:A causal role of coronary thrombosis in evolving myocardial infarction is now widely accepted. Patients recovering from an acute heart attack have a higher risk of dying, or suffering another infarction, than an age-matched non-coronary population. Thrombosis plays a major part in this additional mortality and morbidi...

journal_title：Archives of pathology & laboratory medicine

authors： Smith P

更新日期：1993-01-01 00:00:00

abstract：:The hemostatic response to vascular damage results in the focal generation of thrombin to produce a fibrin/platelet clot at the site of vascular injury. This regulated hemostatic response derives from the assembly and activity of enzyme complexes that are localized to surfaces presented by the vascular damage. The pro...

journal_title：Archives of pathology & laboratory medicine

authors： Mann KG,Lawson JH

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVE:To determine the ability to recover human immunodeficiency virus type 1 (HIV-1) from the plasma and mononuclear cell (MNC) fractions of postmortem blood samples from patients with the acquired immunodeficiency syndrome. DESIGN:Blood was randomly cultured post mortem from 41 patients with the acquired immunod...

journal_title：Archives of pathology & laboratory medicine

authors： Bankowski MJ,Landay AL,Staes B,Shuburg R,Kritzler M,Hajakian V,Kessler H

更新日期：1992-11-01 00:00:00

abstract：:Uterine leiomyoblastomas are neoplasms of smooth muscle origin, which despite their benign histopathologic characteristics, have been shown to invade locally, metastasize, and recur, resulting in the patient's death. In an effort to define possible cellular changes that could explain the disparity between histopatholo...

journal_title：Archives of pathology & laboratory medicine

authors： Kyriazis AP,Kyriazis AA

更新日期：1992-11-01 00:00:00

abstract：:By means of an electrofocusing technique, the serum specimens of pregnant women routinely revealed three bands of alkaline phosphatase (ALP) that were released by placental syncytiotrophoblast, germ cell (ovary), and fetal intestine at pl of 4.73, 4.65, and 4.55, respectively. When defining reference ranges for ostens...

journal_title：Archives of pathology & laboratory medicine

authors： Griffiths J

更新日期：1992-10-01 00:00:00

abstract：:We describe the clinical, radiologic, and pathologic features of four cases of intraosseous lipoma. The patients ranged in age from 37 to 48 years, and three of them were men. Three patients presented with pain; in the fourth patient, the lesion was discovered incidentally. The involved bones were distal radius (in on...

journal_title：Archives of pathology & laboratory medicine

authors： Barcelo M,Pathria MN,Abdul-Karim FW

更新日期：1992-09-01 00:00:00

abstract：:A 25-year-old woman, multigravida, presented with a dark ulcerated tumor of the clitoris. Histologic examination demonstrated an angiokeratoma, a benign telangiectatic vascular tumor. To our knowledge, this is the first report of angiokeratoma of the clitoris and only the fifth describing vascular tumor of this organ....

journal_title：Archives of pathology & laboratory medicine

authors： McNeely TB

更新日期：1992-08-01 00:00:00

abstract：:Over a 3-month period, 61,496 errors were detected in clinical laboratory reports by 631 participants in the College of American Pathologists' 1990 Q-Probes program. Each error detected was defined as an opportunity for improvement. Almost 4% of the detected errors were attributed to nonlaboratory personnel and approx...

journal_title：Archives of pathology & laboratory medicine

authors： Howanitz PJ,Walker K,Bachner P

更新日期：1992-07-01 00:00:00

abstract：:The importance of demonstrating linearity for a clinical chemistry analytical system has caused considerable debate. Disagreement about the way linearity is demonstrated has led to some misunderstanding about just what linearity means to the analytical goals. In many cases where linearity is evaluated by statistical m...

journal_title：Archives of pathology & laboratory medicine

authors： Shires GW

更新日期：1992-07-01 00:00:00

abstract：:Pulmonary and renal infection developed in a 44-year-old Hispanic man due to the fungus Pseudallescheria boydii. Pseudallescheria boydii has been associated with cutaneous infection known as mycetoma but occurs very infrequently in extracutaneous sites. To our knowledge, this is the second reported case of P boydii in...

journal_title：Archives of pathology & laboratory medicine

authors： Scherr GR,Evans SG,Kiyabu MT,Klatt EC

更新日期：1992-05-01 00:00:00

abstract：:In three performance evaluation surveys, panels that consisted of human T-lymphotropic virus type I or type II (HTLV-I/II) antibody-positive and -negative plasma samples were mailed to laboratories that voluntarily participated in the Centers for Disease Control Model Performance Evaluation Program. Donor samples were...

journal_title：Archives of pathology & laboratory medicine

authors： Blumer SO,Hearn TL,Schalla WO,Cross GD,Valdiserri RO

更新日期：1992-05-01 00:00:00

abstract：:In this article, I review the submicroscopic organization of the human spermatozoon, the functional role of its individual organelles in motility, penetrating ability, and fusogenic and fertilizing competence, and its pathology as a cause of male infertility. ...

journal_title：Archives of pathology & laboratory medicine

authors： Zamboni L

更新日期：1992-04-01 00:00:00

abstract：:Ovulation induction protocols for oocyte retrieval have evolved from clomiphene citrate/human menopausal gonadotropins (menotropins) to human menopausal gonadotropins alone and, finally, to a combination of human menopausal gonadotropins and an agonist of gonadotropin-releasing hormone (GnRH-a). The almost abandonment...

journal_title：Archives of pathology & laboratory medicine

authors： Meldrum DR

更新日期：1992-04-01 00:00:00

abstract：:The epidermal growth factor receptor (EGFr) is a membrane-bound glycoprotein that is present in a wide variety of human normal and malignant tissues. In this study EGFr expression in frozen sections of prostate tissue obtained from 40 different surgical specimens was examined immunohistochemically with a well-characte...

journal_title：Archives of pathology & laboratory medicine

authors： Maygarden SJ,Strom S,Ware JL

更新日期：1992-03-01 00:00:00

abstract：:Since carcinomas of the colon or rectum are associated with blood loss, we wondered if complete blood count data were suggestive of iron deficiency in cases of colorectal carcinoma. The mean corpuscular volume and especially the red blood cell distribution width are thought to be more sensitive to early iron deficienc...

journal_title：Archives of pathology & laboratory medicine

authors： Speights VO,Johnson MW,Stoltenberg PH,Rappaport ES,Helbert B,Riggs MW

更新日期：1992-03-01 00:00:00

abstract：:We report a case of rupture of a saccular pulmonary artery aneurysm with fatal hemopericardium in a 29-year-old man who also had persistent ductus arteriosus with severe pulmonary hypertension. Histologic examination of the pulmonary artery showed cystic medionecrosis similar to that observed in patients with ruptured...

journal_title：Archives of pathology & laboratory medicine

authors： Coard KC,Martin MP

更新日期：1992-02-01 00:00:00